Date of Award

7-22-2011

Document Type

Thesis

Degree Name

Master of Science (MS)

Department

Chemistry

First Advisor

Justin D. Fair, Ph.D.

Second Advisor

John T. Wood, Ph.D.

Third Advisor

John C. Woolcock, Ph.D.

Fourth Advisor

Roberta M. Eddy, Ph.D.

Fifth Advisor

Wendy L. Elcesser, Ph.D.

Abstract

The generation and utilization of acyllithium equivalents has been examined. The acyllithium equivalents were generated on compounds containing a remote carbon–carbon π bond five carbons away. This methodology was applied to an unactivated and an activated olefin. The acyllithium equivalent was generated on both species, and it was found that cyclization of the acyllithium onto an activated olefin occurred in good conversion and modest yield.

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